Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906811 | 0.86 | ALDH1A1 (0.68) | MAOBABCG2NR4A1NR4A2NR4A3 | |
| SCHEMBL5906815 | 0.86 | ALDH1A1 (0.68) | MAOBABCG2NR4A1NR4A2NR4A3 | |
| SCHEMBL9741569 | 0.85 | MAOB (0.62) | MAOBABCG2NR4A1NR4A2NR4A3 | |
| SCHEMBL7028240 | 0.77 | MAOB (0.68) | MAOBABCG2NR4A1NR4A2NR4A3 | |
| SCHEMBL8614795 | 0.75 | MAOB (0.76) | MAOBABCG2NPC1RAB9A | |
| SCHEMBL11326878 | 0.74 | NR4A1 (0.70) | MAOBABCG2NR4A1NR4A2NR4A3 | |
| SCHEMBL42302 | 0.74 | MAOB (1.00) | MAOBNR4A1NR4A2NR4A3ALDH1A1 | |
| SCHEMBL31326509 | 0.73 | MAOB (0.65) | MAOBNR4A1NR4A2NR4A3EGFR | |
| SCHEMBL8200793 | 0.73 | MAOB (0.69) | MAOBNR4A1NR4A2NR4A3EGFR | |
| SCHEMBL1443169 | 0.73 | NR4A1 (0.68) | MAOBABCG2NR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110831-A | Antiinflammatory agents; leukotriene antagonists | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-05-05 | — | — | US | disclosed |