Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738700 | 0.95 | AGTR1 (0.39) | SLC33A1AGTR1 | |
| SCHEMBL9738544 | 0.93 | SLC33A1 (0.38) | SLC33A1AGTR1 | |
| SCHEMBL9738567 | 0.91 | AGTR1 (0.41) | AGTR1 | |
| SCHEMBL9738675 | 0.91 | SLC33A1 (0.36) | SLC33A1AGTR1 | |
| SCHEMBL9739973 | 0.89 | AGTR1 (0.47) | AGTR1 | |
| SCHEMBL9738438 | 0.88 | AGTR1 (0.36) | AGTR1 | |
| SCHEMBL9738616 | 0.88 | SLC33A1 (0.36) | SLC33A1AGTR1 | |
| SCHEMBL9738918 | 0.88 | SLC33A1 (0.34) | SLC33A1AGTR1 | |
| SCHEMBL9739505 | 0.86 | RIPK1 (0.37) | SLC33A1 | |
| SCHEMBL9737852 | 0.86 | AGTR1 (0.44) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | claimed |
| WO-1992005161-A1 | 1,3,5-TRISUBSTITUTED-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS | G.D. SEARLE & CO. (US) | 1992-04-02 | — | — | WO | disclosed |