SCHEMBL9738472

SCHEMBL9738472

OCC(O)c1oc(CCc2ccccc2)c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 5/20 0.40
TDP1 Q9NUW8 1/20 0.37
ADRB2 P07550 2/20 0.36
PPARG P37231 1/20 0.35
FAAH O00519 3/20 0.35
HSD17B3 P37058 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9738784 0.86 ABCB1 (0.39) ABCB1ADRB2PPARGFAAHHSD17B3
SCHEMBL9739983 0.78 ABCB1 (0.67) ABCB1ADRB2
E968 SCHEMBL9527553 0.67 TDP1 (0.56) TDP1
Sorbitol SCHEMBL184392 0.64 TDP1 (0.52) TDP1
Hydrogen Peroxide SCHEMBL10839772 0.64 TDP1 (0.71) TDP1
Hydrogen Peroxide SCHEMBL10839871 0.64 TDP1 (0.71) TDP1
SCHEMBL62125 0.61 ALDH1A1 (0.69) TDP1
SCHEMBL9741303 0.61 ALDH1A1 (0.69) TDP1
Benzene SCHEMBL3440179 0.61 ALDH1A1 (0.69) TDP1
SCHEMBL2074517 0.60 TDP1 (0.52) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992017464-A1 PHARMACOLOGICALLY ACTIVE α-AMINOETHYL-2-BENZOFURANE METHANOLS SUBSTITUTED IN POSITION 3 NOE CHRISTIAN R (AT) 1992-10-15 WO disclosed