Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.67 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9746106 | 0.85 | ABCB1 (0.64) | ABCB1ADRB2LMNAKCNH2SMN1; SMN2 | |
| SCHEMBL9739544 | 0.81 | ABCB1 (0.45) | ABCB1ADRB2LMNACYP2D6CYP3A4 | |
| SCHEMBL9739975 | 0.81 | ABCB1 (1.00) | ABCB1ADRB2LMNACYP1A2CYP2D6 | |
| SCHEMBL9738669 | 0.81 | ABCB1 (1.00) | ABCB1ADRB2LMNACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9741907 | 0.80 | ABCB1 (0.98) | ABCB1ADRB2LMNACYP1A2CYP2D6 | |
| SCHEMBL9739041 | 0.79 | ABCB1 (0.65) | ABCB1ADRB2LMNAADRB1SMN1; SMN2 | |
| SCHEMBL9738472 | 0.78 | ABCB1 (0.40) | ABCB1ADRB2 | |
| SCHEMBL9738784 | 0.77 | ABCB1 (0.39) | ABCB1ADRB2HTR2ASMN1; SMN2 | |
| SCHEMBL9739038 | 0.71 | ABCB1 (0.74) | ABCB1LMNAKCNH2SMN1; SMN2 | |
| SCHEMBL9739016 | 0.70 | ABCB1 (1.00) | ABCB1LMNATP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017464-A1 | PHARMACOLOGICALLY ACTIVE α-AMINOETHYL-2-BENZOFURANE METHANOLS SUBSTITUTED IN POSITION 3 | NOE CHRISTIAN R (AT) | 1992-10-15 | — | — | WO | disclosed |