Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27875724 | 0.86 | MAPT (0.60) | MAPTEPAS1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL9513799 | 0.78 | MAPT (0.50) | MAPTEPAS1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL4942989 | 0.78 | ALDH1A1 (0.61) | MAPTEPAS1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL16654980 | 0.76 | MAPT (0.60) | MAPTEPAS1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL16748017 | 0.76 | KMT2A (0.63) | MAPTMAPK1L3MBTL1ALDH1A1TDP1 | |
| SCHEMBL4589497 | 0.75 | EPAS1 (0.71) | MAPTEPAS1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL28523405 | 0.75 | EPAS1 (0.52) | MAPTEPAS1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL4945790 | 0.74 | MAPT (0.58) | MAPTEPAS1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL21463918 | 0.74 | MAPK1 (0.53) | MAPTEPAS1MAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL30615434 | 0.74 | MAPK1 (0.53) | MAPTEPAS1MAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5154751-A | HERBICIDAL UREA COMPOUNDS AND COMPOSITIONS | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |
| EP-0401168-A2 | Herbicides | CIBA-GEIGY AG (CH) | 1990-12-05 | — | — | EP | disclosed |