Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9513771 | 0.84 | ALDH1A1 (0.52) | MAPTALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL9505015 | 0.81 | MAPT (0.46) | MAPTALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL6180492 | 0.80 | TSHR (0.57) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL9738495 | 0.78 | MAPT (0.60) | MAPTALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL27875724 | 0.78 | MAPT (0.60) | MAPTALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL9878202 | 0.78 | ALDH1A1 (0.54) | MAPTALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL10429468 | 0.76 | MAPT (0.56) | MAPTALDH1A1CYP2C19MAPK1TDP1 | |
| SCHEMBL6178841 | 0.73 | MAPK1 (0.51) | MAPTALDH1A1MAPK1TDP1L3MBTL1 | |
| SCHEMBL15741366 | 0.72 | TDP1 (0.46) | MAPTALDH1A1CYP1A2CYP2C19MAPK1 | |
| SCHEMBL30062975 | 0.72 | TDP1 (0.46) | MAPTALDH1A1CYP1A2CYP2C19MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264348-B1 | Ureas | CIBA GEIGY AG (CH) | 1993-12-15 | — | — | EP | disclosed |
| US-4904778-A | Pyrimidine-2-phenylamino derivatives | CIBA-GEIGY CORP. (US) | 1990-02-27 | — | — | US | disclosed |
| US-4802909-A | PLANT GROWTH REGULATORS | CIBA-GEIGY CORPORATION (US) | 1989-02-07 | — | — | US | disclosed |
| EP-0264348-A2 | Ureas | CIBA-GEIGY AG (CH) | 1988-04-20 | — | — | EP | disclosed |