SCHEMBL9738575

SCHEMBL9738575

O=C(Cc1cccc2oc3ccccc3c(=O)c12)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.53
CYP17A1 P05093 1/20 0.48
CYP19A1 P11511 1/20 0.48
CYP11B1 P15538 1/20 0.48
CYP11B2 P19099 1/20 0.48
TTR P02766 4/20 0.48
KDM4E B2RXH2 2/20 0.47
CYP3A4 P08684 2/20 0.47
HSD17B10 Q99714 2/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
GLA P06280 1/20 0.47
HPGD P15428 1/20 0.47
PGAM1 P18669 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
GAA P10253 2/20 0.44
MGAM O43451 1/20 0.44
SI P14410 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7140586 0.87 MAOA (0.57) MAOACYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL27726953 0.82 MAOA (0.55) MAOACYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL13359234 0.80 MAOA (0.64) MAOACYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL27860391 0.77 KDM4E (0.56) MAOACYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL18242476 0.77 MAOA (0.59) MAOACYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL10711560 0.76 MAOA (0.43) MAOACYP19A1KDM4ECYP3A4ALDH1A1
SCHEMBL5425706 0.76 MAOA (0.54) MAOACYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL9367069 0.75 TDP1 (0.56) MAOAKDM4ECYP3A4HSD17B10ALDH1A1
SCHEMBL7943748 0.75 MAOA (0.57) MAOACYP17A1CYP19A1CYP11B1CYP11B2
SCHEMBL9376908 0.75 MAOA (0.57) MAOACYP17A1CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5085886-A Dielectric polymer is formed on substrate from the ether reaction product of dicyclopentadiene and a phenol ALLIED-SIGNAL INC. (US) 1992-02-04 US disclosed