Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 3/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL450088 | 0.79 | KDM1A (0.50) | MAOBNPC1MAPT | |
| SCHEMBL14084323 | 0.77 | NPC1 (0.56) | IDO1ALDH1A1MAPK14PLAUMAOB | |
| SCHEMBL1155300 | 0.77 | ALDH1A1 (0.47) | IDO1ALDH1A1MAPK14PLAUMAOB | |
| SCHEMBL29826329 | 0.75 | KCNH2 (0.34) | ALOX5APFEN1PLAUNPC1RAB9A | |
| SCHEMBL16054616 | 0.73 | CYP11B1 (0.40) | ALDH1A1NPC1RAB9AKMT2AHTR2A | |
| SCHEMBL2291302 | 0.73 | IDO1 (0.52) | IDO1ALDH1A1PARP10NPC1RAB9A | |
| SCHEMBL1761232 | 0.73 | MAOB (0.50) | MAOBNPC1RAB9AFFAR1MAPT | |
| SCHEMBL2292269 | 0.72 | IDO1 (0.47) | IDO1ALDH1A1MAOBPARP10NPC1 | |
| SCHEMBL2287943 | 0.72 | ALDH1A1 (0.57) | IDO1ALDH1A1PARP10NPC1RAB9A | |
| SCHEMBL30331042 | 0.71 | MCL1 (0.56) | IDO1ALDH1A1MAPK14PLAUMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992012133-A2 | ARTHROPODICIDAL CARBOXANILIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-07-23 | — | — | WO | disclosed |