Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23796077 | 0.76 | ALOX5AP (0.48) | KCNH2ALOX5APFEN1ADORA2AFFAR1 | |
| SCHEMBL9738684 | 0.75 | IDO1 (0.40) | ALOX5APFEN1FFAR1PLAUNPC1 | |
| SCHEMBL450088 | 0.74 | KDM1A (0.50) | MRGPRX4NPC1TDP1L3MBTL1 | |
| SCHEMBL31066647 | 0.73 | HTR7 (0.40) | PLAUNPC1RAB9ATDP1L3MBTL1 | |
| SCHEMBL30054255 | 0.72 | CNR1 (0.35) | ALOX5APFEN1PLAUMRGPRX4NPC1 | |
| SCHEMBL16054616 | 0.71 | CYP11B1 (0.40) | NPC1RAB9ATDP1L3MBTL1AR | |
| SCHEMBL29826487 | 0.71 | CYP11B2 (0.33) | FEN1PLAUMRGPRX4NPC1RAB9A | |
| SCHEMBL28289636 | 0.69 | AR (0.39) | L3MBTL1ARGAA | |
| SCHEMBL15923839 | 0.69 | ALDH1A1 (0.44) | L3MBTL1 | |
| SCHEMBL30513214 | 0.68 | AR (0.40) | RAB9AL3MBTL1ARGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4284795-A1 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | Carmot Therapeutics, Inc. (US) | 2023-12-06 | — | — | EP | disclosed |
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |
| WO-2022165076-A1 | GPCR RECEPTOR AGONISTS, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME, AND METHODS FOR THEIR USE | CARMOT THERAPEUTICS, INC. (US) | 2022-08-04 | — | — | WO | disclosed |