Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905167 | 0.82 | HSD17B10 (0.41) | HSD17B10CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL27787172 | 0.82 | ALDH1A1 (0.41) | HSD17B10CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL4885354 | 0.82 | HSD17B10 (0.48) | HSD17B10CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL28853619 | 0.79 | HSD17B10 (0.38) | HSD17B10CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL29958351 | 0.79 | HSD17B10 (0.38) | HSD17B10CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL4949003 | 0.79 | KMT2A (0.46) | HSD17B10CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL26963211 | 0.78 | HSD17B10 (0.42) | HSD17B10CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL28009715 | 0.78 | KDM4E (0.42) | HSD17B10CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL29450079 | 0.77 | HSD17B10 (0.47) | HSD17B10CYP1A2KDM4EALDH1A1HPGD | |
| SCHEMBL186130 | 0.77 | HSD17B10 (0.47) | HSD17B10CYP1A2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139909-A | Unsymmetrical | XEROX CORPORATION (US) | 1992-08-18 | — | — | US | disclosed |