SCHEMBL4885354

SCHEMBL4885354

O=C(O)c1c(C(=O)O)c2c(C(=O)O)c(C(=O)O)c(C(=O)O)c3c4cccc5cccc(c(c1C(=O)O)c23)c54

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 6/20 0.48
ALDH1A1 P00352 6/20 0.48
KDM4E B2RXH2 6/20 0.48
KMT2A Q03164 4/20 0.48
HPGD P15428 4/20 0.48
CYP1A2 P05177 4/20 0.48
MEN1 O00255 3/20 0.48
GLA P06280 2/20 0.48
CYP2C19 P33261 1/20 0.48
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
CDC25B P30305 1/20 0.43
CA12 O43570 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28009715 0.91 KDM4E (0.42) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL4949003 0.89 KMT2A (0.46) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL2078836 0.88 HSD17B10 (0.40) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL10802779 0.88 KMT2A (0.40) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL11060599 0.86 LMNA (0.43) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL29450079 0.83 HSD17B10 (0.47) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL28062062 0.83 HSD17B10 (0.47) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL31542978 0.83 HSD17B10 (0.47) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL186130 0.83 HSD17B10 (0.47) HSD17B10ALDH1A1KDM4EKMT2AHPGD
SCHEMBL9738951 0.82 HSD17B10 (0.41) HSD17B10ALDH1A1KDM4EKMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104557959-A Benzoperylene imide derivatives, and preparation method and application thereof UNIV FUZHOU 2015-04-29 CN claimed
US-20080187505-A1 Use of fluorescent polymers for the treatment of human hair PROCTER & GAMBLE COMPANY, THE 2008-08-07 US claimed
EP-1671674-B1 Use of fluorescent polymers for the treatment of human hair WELLA AG (DE) 2007-10-17 EP claimed
EP-1671674-A1 Use of fluorescent polymers for the treatment of human hair Wella Aktiengesellschaft (DE) 2006-06-21 EP claimed
CN-104557959-B Benzoperylene imide derivatives, and preparation method and application thereof 福州大学 2017-05-10 CN disclosed
CN-104557959-A Benzoperylene imide derivatives, and preparation method and application thereof UNIV FUZHOU 2015-04-29 CN disclosed
US-20080187505-A1 Use of fluorescent polymers for the treatment of human hair PROCTER & GAMBLE COMPANY, THE 2008-08-07 US disclosed
US-20080187505-A1 Use of fluorescent polymers for the treatment of human hair PROCTER & GAMBLE COMPANY, THE 2008-08-07 US disclosed
EP-1671674-B1 Use of fluorescent polymers for the treatment of human hair WELLA AG (DE) 2007-10-17 EP disclosed
EP-1671674-A1 Use of fluorescent polymers for the treatment of human hair Wella Aktiengesellschaft (DE) 2006-06-21 EP disclosed
EP-1671674-A1 Use of fluorescent polymers for the treatment of human hair Wella Aktiengesellschaft (DE) 2006-06-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080187505-A1 Use of fluorescent polymers for the treatment of human hair FHIT, SUCLG1, PBRM1 HSD17B10 1065/4885ALDH1A1 1111/4885KDM4E 1925/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.