Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | QPCT | Q16769 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740244 | 0.80 | MAPT (0.58) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL9740176 | 0.76 | IDH1 (0.46) | KMT2AMEN1GAAKDM4EMAPT | |
| SCHEMBL30358933 | 0.72 | MEN1 (0.60) | KMT2AMEN1HIF1AGAAKDM4E | |
| SCHEMBL10388545 | 0.72 | HIF1A (0.74) | KMT2AMEN1HIF1AGAAKDM4E | |
| SCHEMBL30287924 | 0.72 | HIF1A (0.74) | KMT2AMEN1HIF1AGAAKDM4E | |
| SCHEMBL3267065 | 0.72 | MEN1 (0.53) | KMT2AMEN1HIF1AGAAKDM4E | |
| SCHEMBL6483812 | 0.71 | MEN1 (0.59) | KMT2AMEN1HIF1AGAAKDM4E | |
| SCHEMBL28906915 | 0.71 | HIF1A (0.64) | KMT2AMEN1HIF1AGAAKDM4E | |
| SCHEMBL5713573 | 0.70 | TUBB4A (0.61) | KMT2AMEN1HIF1AGAAKDM4E | |
| SCHEMBL9739054 | 0.70 | IDO1 (0.44) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |