Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 12/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727370 | 0.77 | DNM1 (0.42) | DNM1PLA2G1BPLA2G2AMEN1KMT2A | |
| SCHEMBL11820748 | 0.77 | DNM1 (0.42) | DNM1PLA2G1BPLA2G2AMEN1KMT2A | |
| SCHEMBL6156030 | 0.77 | DNM1 (0.42) | DNM1PLA2G1BPLA2G2AMEN1KMT2A | |
| SCHEMBL9547907 | 0.77 | DNM1 (0.42) | DNM1PLA2G1BPLA2G2AMEN1KMT2A | |
| SCHEMBL29429116 | 0.77 | DNM1 (0.42) | DNM1PLA2G1BPLA2G2AMEN1KMT2A | |
| SCHEMBL10603507 | 0.77 | DNM1 (0.42) | DNM1PLA2G1BPLA2G2AMEN1KMT2A | |
| SCHEMBL1039266 | 0.76 | DNM1 (0.46) | DNM1PLA2G1BPLA2G2AOPRM1MEN1 | |
| SCHEMBL6366975 | 0.76 | DNM1 (0.46) | DNM1PLA2G1BPLA2G2AOPRM1MEN1 | |
| SCHEMBL11315678 | 0.73 | OPRM1 (0.48) | PLA2G1BPLA2G2AOPRM1SPHK1 | |
| SCHEMBL9873123 | 0.73 | OPRM1 (0.46) | DNM1PLA2G1BPLA2G2AOPRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151522-A | Condensation of imidazoline compounds with acrylic acid, methacrylic acid or maleic acid | CHEMISCHES INSTITUT SCHAEFER AG (CH) | 1992-09-29 | — | — | US | disclosed |
| US-5049315-A | Polycarboxylic acid imidazolines, process for the preparation thereof and cleaning agents containing them | CHEMISCHES INSTUTUT SCHAEFER AG (DE) | 1991-09-17 | — | — | US | disclosed |