Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HCN4 | Q9Y3Q4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9740815 | 0.99 | ABCG2 (0.46) | ABCG2ABCB1HRH3KCNJ1KCNH2 | |
| SCHEMBL9739319 | 0.89 | SMN1; SMN2 (0.42) | ABCG2ABCB1HRH3MAPTGAA | |
| SCHEMBL9740418 | 0.89 | ABCB1 (0.46) | ABCG2ABCB1HRH3MAPTGAA | |
| SCHEMBL9739180 | 0.88 | SMN1; SMN2 (0.43) | ABCG2ABCB1MAPTGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9739564 | 0.88 | CYP3A4 (0.41) | ABCG2ABCB1HRH3MAPTGAA | |
| Hydrochloric Acid SCHEMBL9740153 | 0.88 | ABCB1 (0.45) | ABCG2ABCB1HRH3MAPTGAA | |
| SCHEMBL9740219 | 0.88 | HCN4 (0.49) | MAPTGAAALDH1A1KDM4EPOLB | |
| SCHEMBL9739355 | 0.88 | SMN1; SMN2 (0.42) | GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL9740267 | 0.88 | HRH3 (0.44) | HRH3KCNJ1KCNH2ALDH1A1MEN1 | |
| SCHEMBL9740525 | 0.87 | HCN4 (0.49) | MAPTGAAALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| EP-0224794-B1 | CYCLIC AMINE DERIVATIVES, MEDICINES CONTAINING THESE COMPOUNDS AND PROCESS FOR THEIR PREPARATION | Dr. Karl Thomae GmbH (DE) | 1990-09-12 | — | — | EP | disclosed |