Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739433 | 1.00 | GPR55 (0.33) | GPR55RARARARBRARGKDM4E | |
| SCHEMBL9739284 | 0.88 | ALDH1A1 (0.36) | GPR55RARARARBRARGKDM4E | |
| SCHEMBL9740518 | 0.88 | GPR55 (0.34) | GPR55RARARARBRARGPTGS2 | |
| SCHEMBL9740526 | 0.88 | GPR55 (0.34) | GPR55RARARARBRARGPTGS2 | |
| SCHEMBL9740189 | 0.76 | HMGCR (0.49) | ALDH1A1PTGS2 | |
| SCHEMBL9740191 | 0.76 | HMGCR (0.49) | ALDH1A1PTGS2 | |
| SCHEMBL9739956 | 0.75 | GPR55 (0.36) | GPR55RARARARBRARGPTGS2 | |
| SCHEMBL9739082 | 0.75 | HMGCR (0.35) | — | |
| SCHEMBL9747836 | 0.74 | HMGCR (0.43) | — | |
| SCHEMBL9747845 | 0.74 | HMGCR (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5110825-A | Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A; anticholesterol, antilipemic, antiatherosclerotic | SHIONOGI & CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |
| EP-0435322-A2 | Benzofuran derivatives | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) | 1991-07-03 | — | — | EP | disclosed |