Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741890 | 0.81 | CYP19A1 (0.38) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL9741961 | 0.76 | DAO (0.32) | — | |
| SCHEMBL1966772 | 0.76 | CA1 (0.39) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL9740698 | 0.71 | KDM4E (0.37) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL1969418 | 0.70 | KDM4E (0.34) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL29793327 | 0.67 | ACHE (0.52) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL1635785 | 0.67 | ACHE (0.52) | KDM4EMEN1POLBGAAMAPT | |
| SCHEMBL9739991 | 0.67 | NQO2 (0.39) | KDM4EGAAACHENQO2 | |
| SCHEMBL9738931 | 0.67 | CYP19A1 (0.39) | KDM4EMAPTACHECYP19A1NQO2 | |
| SCHEMBL9740213 | 0.66 | ERN1 (0.34) | MAPTNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |