Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1539241 | 0.72 | CA1 (0.39) | KDM4EMEN1MAPTKMT2AHPGD | |
| SCHEMBL1966772 | 0.72 | CA1 (0.39) | KDM4EMEN1MAPTKMT2APOLB | |
| SCHEMBL6001048 | 0.72 | PDPK1 (0.35) | MEN1KMT2ACYP2C9 | |
| SCHEMBL9739481 | 0.71 | KDM4E (0.38) | KDM4EMEN1MAPTKMT2APOLB | |
| SCHEMBL1969418 | 0.71 | KDM4E (0.34) | KDM4EMEN1MAPTKMT2APOLB | |
| SCHEMBL9739295 | 0.71 | TUBB4A (0.33) | KDM4EMAPTCYP19A1NQO2HPGD | |
| SCHEMBL9741890 | 0.71 | CYP19A1 (0.38) | KDM4EMEN1MAPTKMT2APOLB | |
| SCHEMBL9738931 | 0.63 | CYP19A1 (0.39) | KDM4EMAPTCYP19A1NQO2HPGD | |
| SCHEMBL9739991 | 0.63 | NQO2 (0.39) | KDM4EGAANQO2HPGDCA12 | |
| SCHEMBL7456122 | 0.62 | MEN1 (0.32) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |