Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | IDO1 | P14902 | 3/20 | 0.33 |
| ▸ | TDO2 | P48775 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740551 | 0.81 | KDM4E (0.35) | CA1CA2CA4ALDH1A1KDM4E | |
| SCHEMBL1539240 | 0.74 | ABCG2 (0.41) | CA1CA2CA4CA6ALDH1A1 | |
| SCHEMBL38660362 | 0.71 | TUBB4A (0.47) | MAPTTDP1 | |
| SCHEMBL2085433 | 0.71 | TUBB4A (0.47) | MAPTTDP1 | |
| SCHEMBL9740158 | 0.69 | KDM4E (0.41) | CYP19A1NQO2CA1CA2CA4 | |
| SCHEMBL16641096 | 0.69 | ALDH1A1 (0.50) | CYP19A1NQO2CA1CA2CA4 | |
| SCHEMBL6181005 | 0.69 | KDM4E (0.39) | CYP19A1NQO2ALDH1A1KDM4EMAPT | |
| SCHEMBL30701949 | 0.68 | CA9 (0.50) | CYP19A1CA1CA2CA4ALDH1A1 | |
| SCHEMBL3674074 | 0.68 | CA9 (0.50) | CYP19A1CA1CA2CA4ALDH1A1 | |
| SCHEMBL9959635 | 0.68 | ALDH1A1 (0.47) | CYP19A1NQO2CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |