Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 7/20 | 0.60 |
| ▸ | CPA3 | P15088 | 2/20 | 0.60 |
| ▸ | CPB1 | P15086 | 1/20 | 0.60 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.50 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7280261 | 0.82 | CPA1 (0.66) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL9554494 | 0.79 | CPA1 (0.64) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL9554487 | 0.79 | CPA1 (0.64) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL8006913 | 0.79 | MME (0.47) | CPA1MAPTMMEMEN1KMT2A | |
| SCHEMBL9222947 | 0.79 | CPA1 (0.71) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL9554964 | 0.79 | CPA1 (0.71) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7278058 | 0.79 | CPA1 (0.71) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL11478326 | 0.78 | CYP1A2 (0.52) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL3844932 | 0.78 | KMT2A (0.70) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL10076047 | 0.77 | CPA1 (0.70) | CPA1CPA3CPB1CPB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104869-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0427939-A2 | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1991-05-22 | — | — | EP | disclosed |