Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA1 | P15085 | 6/20 | 0.66 |
| ▸ | CPA3 | P15088 | 3/20 | 0.66 |
| ▸ | CPB1 | P15086 | 1/20 | 0.66 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | MME | P08473 | 2/20 | 0.57 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | FCER2 | P06734 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 2/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | ECE1 | P42892 | 1/20 | 0.55 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.54 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739581 | 0.82 | CPA1 (0.60) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL3844932 | 0.81 | KMT2A (0.70) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL29889513 | 0.81 | TRPA1 (0.56) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7322470 | 0.80 | CPA1 (0.72) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7322467 | 0.80 | CPA1 (0.72) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL2807018 | 0.80 | MME (0.67) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7280073 | 0.80 | CPA1 (0.57) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL7434721 | 0.80 | CPA1 (0.57) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL5688996 | 0.80 | CPA1 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 | |
| SCHEMBL1915564 | 0.80 | CPA1 (1.00) | CPA1CPA3CPB1CPB2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5258362-A | Enzyme inhibitors, amides with oxetane ring | ABBOTT LABORATORIES (US) | 1993-11-02 | — | — | US | disclosed |
| WO-1992022313-A1 | RENIN INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1992-12-23 | — | — | WO | disclosed |
| WO-1989010751-A1 | FUNCTIONALIZED PEPTIDYL AMINODIOLS AND -TRIOLS | ABBOTT LABORATORIES (US) | 1989-11-16 | — | — | WO | disclosed |
| EP-0341602-A2 | Renin-inhibiting functionalized peptidyl aminodiols and - triols | ABBOTT LABORATORIES (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |