Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217084 | 0.95 | ADRA1B (0.46) | ADRA1BABCB1DRD4DRD3DRD2 | |
| SCHEMBL9739808 | 0.91 | HRH3 (0.41) | HRH3 | |
| SCHEMBL9740374 | 0.91 | HRH3 (0.41) | ABCB1HRH3 | |
| SCHEMBL9739322 | 0.89 | HRH3 (0.42) | ABCB1HRH3 | |
| SCHEMBL9739061 | 0.89 | ACHE (0.40) | ADRA1BABCB1DRD4DRD3DRD2 | |
| SCHEMBL9207830 | 0.88 | HRH3 (0.51) | ADRA1BHRH3DRD4DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL9213538 | 0.87 | HRH3 (0.50) | ADRA1BHRH3DRD4DRD3DRD2 | |
| SCHEMBL9206439 | 0.87 | ABCB1 (0.49) | ADRA1BABCB1HRH3DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL9213140 | 0.86 | ABCB1 (0.48) | ADRA1BABCB1DRD4DRD3HTR1A | |
| SCHEMBL9740185 | 0.85 | HRH3 (0.51) | ABCB1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |