Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.32 |
| ▸ | WNT3A | P56704 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739453 | 0.81 | GPR84 (0.31) | — | |
| SCHEMBL67912 | 0.81 | KIF11 (0.41) | KIF11CA2ALDH1A1 | |
| SCHEMBL68476 | 0.69 | GPR84 (0.41) | KIF11CA2ALDH1A1 | |
| SCHEMBL7281525 | 0.69 | SMN1; SMN2 (0.42) | AXLKIF11CES1KDM4ESMN1; SMN2 | |
| SCHEMBL558190 | 0.68 | AXL (0.47) | AXLKIF11CES1KDM4ESMN1; SMN2 | |
| SCHEMBL1539241 | 0.65 | CA1 (0.39) | KDM4ESMN1; SMN2HSD17B10CA2MEN1 | |
| SCHEMBL27479367 | 0.64 | HTR2C (0.34) | — | |
| SCHEMBL30225674 | 0.64 | AXL (0.52) | AXLKIF11KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL826095 | 0.64 | AXL (0.52) | AXLKIF11KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL455644 | 0.64 | CES1 (0.34) | AXLKIF11CES1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |