Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TLR3 | O15455 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741124 | 0.86 | HTR2B (0.33) | SMN1; SMN2LMNAHTTALDH1A1MEN1 | |
| SCHEMBL9736573 | 0.84 | MAPT (0.36) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL9740322 | 0.84 | ABCB1 (0.39) | LMNA | |
| SCHEMBL9739194 | 0.83 | MAPT (0.35) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL9739212 | 0.83 | IDO1 (0.35) | MAPTSMN1; SMN2LMNAALDH1A1MEN1 | |
| SCHEMBL8538165 | 0.81 | MAPT (0.35) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL9735242 | 0.80 | MAPT (0.33) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL7331791 | 0.76 | ABCC9 (0.40) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL7332446 | 0.76 | MAPT (0.33) | MAPTSMN1; SMN2LMNAHTTALDH1A1 | |
| SCHEMBL8138332 | 0.74 | TLR3 (0.35) | MAPTSMN1; SMN2LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |