Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 7/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740322 | 0.86 | ABCB1 (0.39) | LMNA | |
| SCHEMBL9739833 | 0.86 | MAPT (0.37) | TRPV1ALDH1A1LMNAHTTPKM | |
| SCHEMBL9739212 | 0.85 | IDO1 (0.35) | TRPV1IDO1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9735180 | 0.83 | HTR2B (0.33) | HTR2BTRPV1IDO1ALDH1A1PKM | |
| SCHEMBL9740513 | 0.82 | HTR2B (0.33) | HTR2BTRPV1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL9737313 | 0.79 | PKM (0.31) | HTR2BPKMSMN1; SMN2HIF1ABACE1 | |
| SCHEMBL8541429 | 0.79 | MAPT (0.33) | HTR2BPKMSMN1; SMN2HIF1A | |
| SCHEMBL7332443 | 0.75 | ABCC9 (0.36) | HTR2BTRPV1ALDH1A1LMNAPKM | |
| SCHEMBL9150597 | 0.74 | TRPV1 (0.34) | HTR2BTRPV1ALDH1A1LMNAHTT | |
| SCHEMBL7332464 | 0.73 | HTR2B (0.34) | HTR2BPKMSMN1; SMN2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130322-A | CHROMAN DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1992-07-14 | — | — | US | disclosed |