SCHEMBL9739889

SCHEMBL9739889

CC(C)NCC(O)c1oc2ccccc2c1CCc1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 7/20 0.71
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
PPARG P37231 1/20 0.37
MEN1 O00255 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
KMT2A Q03164 1/20 0.37
HIF1A Q16665 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9744499 0.99 ABCB1 (0.69) ABCB1ADRB2ADRB1MTNR1AMTNR1B
SCHEMBL9739542 0.84 ABCB1 (0.69) ABCB1ADRB2ADRB1MTNR1AMTNR1B
SCHEMBL9738669 0.83 ABCB1 (1.00) ABCB1ADRB2ADRB1MTNR1AMTNR1B
SCHEMBL9739975 0.83 ABCB1 (1.00) ABCB1ADRB2ADRB1MTNR1AMTNR1B
Hydrochloric Acid SCHEMBL9741907 0.82 ABCB1 (0.98) ABCB1ADRB2ADRB1MTNR1AMTNR1B
SCHEMBL9738780 0.80 ABCB1 (0.64) ABCB1MTNR1AMTNR1BNPC1RAB9A
SCHEMBL9739013 0.74 ABCB1 (0.56) ABCB1MTNR1AMTNR1BNPC1RAB9A
SCHEMBL8083192 0.69 TSHR (0.57) ADRB2ADRB1MEN1CYP1A2CYP2D6
SCHEMBL9739016 0.68 ABCB1 (1.00) ABCB1L3MBTL1
SCHEMBL721278 0.66 ABCB1 (0.63) ABCB1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992017464-A1 PHARMACOLOGICALLY ACTIVE α-AMINOETHYL-2-BENZOFURANE METHANOLS SUBSTITUTED IN POSITION 3 NOE CHRISTIAN R (AT) 1992-10-15 WO disclosed