Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738716 | 0.72 | PARP1 (0.47) | — | |
| SCHEMBL15334780 | 0.68 | DYRK1A (0.42) | TSHRDYRK1A | |
| SCHEMBL6366229 | 0.62 | TSHR (0.46) | TSHRMEN1KMT2APDE3BPDE3A | |
| SCHEMBL11831269 | 0.61 | TSHR (0.35) | TSHRDYRK1A | |
| SCHEMBL14556065 | 0.60 | P2RX7 (0.43) | TSHR | |
| SCHEMBL13748893 | 0.59 | TSHR (0.33) | TSHR | |
| SCHEMBL12190615 | 0.58 | PDE3B (0.37) | TSHRPDE3BPDE3A | |
| SCHEMBL12862602 | 0.56 | TSHR (1.00) | TSHRPDE3BPDE3A | |
| SCHEMBL16885274 | 0.56 | KDM4E (0.38) | TSHRPDE3BPDE3A | |
| SCHEMBL5307611 | 0.56 | TSHR (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006979-A1 | NEW DIAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-04-30 | — | — | WO | disclosed |