Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739181 | 0.75 | ALDH1A1 (0.37) | MAPTLMNAALDH1A1HPGDRXFP1 | |
| SCHEMBL23885984 | 0.72 | PARP1 (0.54) | PARP1MAPTRETKDRAR | |
| SCHEMBL9740205 | 0.72 | TSHR (0.39) | — | |
| SCHEMBL17285575 | 0.70 | ALDH1A1 (0.71) | PARP1MAPTRETKDRAR | |
| SCHEMBL7122967 | 0.69 | AR (0.77) | PARP1ARLMNACYP2C9 | |
| SCHEMBL4439381 | 0.64 | PARP1 (1.00) | PARP1ARLMNA | |
| SCHEMBL4555471 | 0.62 | PARP1 (1.00) | PARP1 | |
| SCHEMBL6607927 | 0.62 | PARP1 (0.45) | PARP1KDRARLMNAALDH1A1 | |
| SCHEMBL9375100 | 0.62 | PARP1 (0.60) | PARP1ARLMNAALDH1A1HPGD | |
| SCHEMBL9374755 | 0.62 | TSHR (0.47) | PARP1MAPTARLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006979-A1 | NEW DIAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1992-04-30 | — | — | WO | disclosed |