Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739954 | 0.81 | ALDH1A1 (0.37) | PDE3BPDE3ANQO2CYP1A2ALDH1A1 | |
| SCHEMBL9740846 | 0.79 | RXFP1 (0.38) | NQO2ALDH1A1MAPT | |
| SCHEMBL5865329 | 0.73 | KDM4E (0.46) | NQO2ALDH1A1CYP3A4CA12CA1 | |
| SCHEMBL4477746 | 0.71 | CA12 (0.41) | NQO2ALDH1A1CYP3A4CA12CA1 | |
| SCHEMBL1748919 | 0.71 | MEN1 (0.48) | PDE3BPDE3ANQO2CYP1A2ALDH1A1 | |
| Difucol Hexamethyl Ether SCHEMBL505203 | 0.69 | CYP1A2 (0.60) | NQO2CYP1A2ALDH1A1CYP3A4CA12 | |
| SCHEMBL315575 | 0.68 | AXL (0.53) | PDE3BPDE3ACYP1A2ALDH1A1CA2 | |
| SCHEMBL577336 | 0.67 | EHMT2 (0.48) | PDE3BPDE3ANQO2ALDH1A1CYP3A4 | |
| SCHEMBL27458974 | 0.67 | PDE3B (0.40) | PDE3BPDE3ANQO2CYP1A2ALDH1A1 | |
| SCHEMBL8860398 | 0.67 | CA12 (0.39) | PDE3BPDE3ANQO2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |