Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.37 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740260 | 0.79 | PDE3B (0.40) | ALDH1A1MAPTNQO2 | |
| SCHEMBL2301175 | 0.72 | BRD4 (0.43) | RXFP1ALDH1A1PRNPMAPTNPSR1 | |
| SCHEMBL9739954 | 0.72 | ALDH1A1 (0.37) | ALDH1A1MAPTNQO2MAOBAXL | |
| SCHEMBL5865329 | 0.72 | KDM4E (0.46) | ALDH1A1MAPTNQO2POLB | |
| SCHEMBL9740482 | 0.70 | CA2 (0.44) | ALDH1A1MAPTNQO2AXLGRIN2D | |
| SCHEMBL4477746 | 0.69 | CA12 (0.41) | ALDH1A1MAPTNQO2ALOX15ALOX12 | |
| SCHEMBL14995475 | 0.69 | AXL (0.51) | RXFP1ALDH1A1PRNPMAPTNPSR1 | |
| SCHEMBL7271023 | 0.68 | CA12 (0.43) | RXFP1MAPTPIM1NQO2ERN1 | |
| SCHEMBL8158740 | 0.66 | ERN1 (0.44) | RXFP1ALDH1A1PRNPMAPTNPSR1 | |
| SCHEMBL1318287 | 0.66 | RXFP1 (0.37) | RXFP1ALDH1A1PRNPMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |