SCHEMBL9740289

SCHEMBL9740289

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)OC(=O)N1CCC(=O)CC1)C(=O)N[C@H](CC1CCCCC1)[C@H](O)c1ccco1

nearest known ligand 0.57

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 20/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9740293 1.00 REN (0.57) REN
SCHEMBL9740840 0.89 REN (0.55) REN
SCHEMBL9740837 0.89 REN (0.55) REN
SCHEMBL7269492 0.82 REN (0.57) REN
SCHEMBL7269499 0.82 REN (0.57) REN
SCHEMBL9725895 0.79 REN (0.61) REN
SCHEMBL9725900 0.79 REN (0.61) REN
SCHEMBL9555781 0.78 REN (0.52) REN
SCHEMBL7300500 0.78 REN (0.61) REN
SCHEMBL7300506 0.78 REN (0.61) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104869-A Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1992-04-14 US claimed
US-5104869-A Renin inhibitors AMERICAN CYANAMID COMPANY (US) 1992-04-14 US disclosed