Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 10/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740437 | 1.00 | GRIN2B (0.47) | GRIN2BGRIN1SMN1; SMN2LMNASLC6A4 | |
| SCHEMBL9211361 | 0.75 | NAMPT (0.42) | SMN1; SMN2 | |
| SCHEMBL9211552 | 0.75 | NAMPT (0.42) | SMN1; SMN2 | |
| SCHEMBL9595523 | 0.73 | GRIN2B (0.57) | GRIN2BGRIN1SMN1; SMN2LMNA | |
| SCHEMBL9595519 | 0.73 | GRIN2B (0.57) | GRIN2BGRIN1SMN1; SMN2LMNA | |
| SCHEMBL8361629 | 0.69 | LOXL2 (0.46) | SMN1; SMN2LMNASLC6A4 | |
| SCHEMBL20040085 | 0.67 | LMNA (0.54) | SMN1; SMN2LMNA | |
| SCHEMBL9740443 | 0.67 | MEN1 (0.46) | SMN1; SMN2LMNA | |
| SCHEMBL456941 | 0.65 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL17196594 | 0.65 | GRIN2B (1.00) | GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166347-A | Hypotensive agents, cardiovascular disorders, antiischemic agents and anticoagulants | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-11-24 | — | — | US | disclosed |