Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15067272 | 0.81 | KDM4E (0.37) | PDE4BTSHRKDM4EKMT2ACA1 | |
| SCHEMBL8674 | 0.80 | CA2 (0.46) | PDE4BPOLBTSHRMAPK1KDM4E | |
| SCHEMBL15066779 | 0.79 | KDM4E (0.36) | PDE4BTSHRKDM4EKMT2ACA1 | |
| SCHEMBL12485371 | 0.78 | MEN1 (0.31) | MAPK1KMT2A | |
| SCHEMBL15066549 | 0.78 | KDM4E (0.32) | NFE2L2KDM4EKMT2A | |
| SCHEMBL15067412 | 0.78 | KDM4E (0.32) | KDM4EKMT2A | |
| SCHEMBL15067290 | 0.78 | KDM4E (0.32) | KDM4EKMT2A | |
| SCHEMBL15067717 | 0.78 | KDM4E (0.32) | NFE2L2KDM4EKMT2A | |
| SCHEMBL27494520 | 0.78 | CA2 (0.43) | POLBTSHRMAPK1KDM4ECA1 | |
| SCHEMBL28251730 | 0.78 | CA2 (0.43) | POLBTSHRMAPK1KDM4ECA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |