Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL970304 | 0.81 | LCK (0.42) | LDHASRRFFAR3LCKPPARD | |
| SCHEMBL935296 | 0.78 | MGAM (0.44) | ALDH1A1TSHRKMT2AZDHHC7RECQL | |
| SCHEMBL15823996 | 0.78 | LMNA (0.43) | FFAR3PPARDALDH1A1TSHRKMT2A | |
| SCHEMBL4467943 | 0.75 | GAA (0.58) | ALDH1A1KMT2AZDHHC7 | |
| SCHEMBL26941934 | 0.74 | — | — | |
| SCHEMBL1435946 | 0.74 | — | — | |
| SCHEMBL2021291 | 0.74 | USP2 (0.44) | LDHASRRFFAR3TSHRKMT2A | |
| SCHEMBL15537177 | 0.74 | — | — | |
| SCHEMBL6266183 | 0.73 | LCK (0.48) | LDHASRRLCKPPARDZDHHC20 | |
| SCHEMBL1730691 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158406-B2 | reduction of keto compounds, in particular of 4-halo-3-oxobutyric acid esters, to the corresponding R-alcohols or S-4-halo-3-hydroxybutyric acid esters, respectively, using an R-specific oxidoreductase in the presence of a cofactor such as NAD(P)H | IEP GMBH (DE) | 2012-04-17 | — | — | US | claimed |
| EP-1926821-B1 | Method of enantioselective enzymatic reduction of keto compounds | IEP GMBH (DE) | 2011-04-20 | — | — | EP | claimed |
| EP-1851322-B1 | METHOD FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GMBH (DE) | 2009-10-21 | — | — | EP | claimed |
| US-20080233619-A1 | Process For the Enantioselective Enzymatic Reduction of Keto Compounds | IEP GMBH (DE) | 2008-09-25 | — | — | US | claimed |
| US-20080153140-A1 | Method for the Enantioselective Enzymatic Reduction of Keto Compounds | IEP GMBH (DE) | 2008-06-26 | — | — | US | claimed |
| EP-1926821-A1 | METHOD OF ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GmbH (DE) | 2008-06-04 | — | — | EP | claimed |
| EP-1851322-A1 | METHOD FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GmbH (DE) | 2007-11-07 | — | — | EP | claimed |
| WO-2007036257-A1 | METHOD OF ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GMBH (DE) | 2007-04-05 | — | — | WO | claimed |
| WO-2006087235-A1 | METHOD FOR THE ENANTIOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | IEP GMBH (DE) | 2006-08-24 | — | — | WO | claimed |
| US-7056540-B2 | Enzymatic process for the preparation of optically active alcohols from ketones using tuberous root Daucus carota | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-06-06 | — | — | US | claimed |
| US-20040082043-A1 | Enzymatic process for the preparation of optically active alcohols from ketones using tuberous root daucus carota | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-04-29 | — | — | US | claimed |
| EP-0902016-B1 | A process and intermediate compounds for the preparation of amlodipine benzene sulphonate | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2002-05-02 | — | — | EP | claimed |
| US-6046337-A | Process for the preparation of a dihydropyridine derivative | EGIS GYOGYSZERGYAR RT. (HU) | 2000-04-04 | — | — | US | claimed |
| EP-0902016-A1 | A process and intermediate compounds for the preparation of amlodipine benzene sulphonate | EGIS GYOGYSZERGYAR (HU) | 1999-03-17 | — | — | EP | claimed |
| EP-0902016-A2 | A process and intermediate compounds for the preparation of amlodipine benzene sulphonate | EGIS GYOGYSZERGYAR RT. (HU) | 1999-03-17 | — | — | EP | claimed |
| EP-2858999-B1 | AMIDES OF 2-AMINO-4-ARYLTHIAZOLE COMPOUNDS AND THEIR SALTS | GLENMARK PHARMACEUTICALS SA (CH) | 2017-05-10 | — | — | EP | disclosed |
| EP-2403953-B1 | METHOD FOR STEREOSELECTIVE ENZYMATIC REDUCTION OF KETO COMPOUNDS | CAMBREX IEP GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| US-4421912-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-12-20 | — | — | US | disclosed |
| US-4379924-A | Cephalosporin derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-04-12 | — | — | US | disclosed |
| US-4080498-A | ANTIBIOTICS, BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1978-03-21 | — | — | US | disclosed |