Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738928 | 0.95 | ABCB1 (0.42) | HRH3ABCB1CYP2D6MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9739352 | 0.88 | ADRA1B (0.39) | HRH3ABCB1CYP2D6MEN1ALDH1A1 | |
| SCHEMBL9742239 | 0.87 | ADRA1B (0.45) | HRH3ABCB1CYP2D6MEN1ALDH1A1 | |
| SCHEMBL9740162 | 0.84 | HRH3 (0.49) | HRH3ABCB1CYP2D6MEN1ALDH1A1 | |
| SCHEMBL9739322 | 0.83 | HRH3 (0.42) | HRH3ABCB1 | |
| SCHEMBL9207879 | 0.83 | KMT2A (0.33) | MEN1ALDH1A1KMT2AMAPTHCN4 | |
| Hydrochloric Acid SCHEMBL9741913 | 0.82 | HRH3 (0.39) | HRH3ABCB1CYP2D6MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9740876 | 0.80 | HRH3 (0.47) | HRH3ABCB1CYP2D6MEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9740789 | 0.79 | KDM4E (0.48) | HRH3ABCB1ALDH1A1KMT2ACYP3A4 | |
| SCHEMBL9740254 | 0.79 | HRH3 (0.44) | HRH3ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |