Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847915 | 0.92 | MEN1 (0.35) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL1551187 | 0.77 | AHR (0.43) | ALDH1A1IDO1TSHRCYP3A4 | |
| SCHEMBL12446580 | 0.76 | MEN1 (0.38) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL29957252 | 0.76 | MEN1 (0.38) | MEN1KMT2AALDH1A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL11624287 | 0.75 | AHR (0.42) | ALDH1A1IDO1TSHRCYP3A4 | |
| SCHEMBL1578248 | 0.74 | AHR (0.37) | ALDH1A1IDO1TSHRCYP3A4 | |
| SCHEMBL14739391 | 0.72 | — | — | |
| SCHEMBL13751191 | 0.71 | ACHE (0.37) | TSHRSLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7253226 | 0.70 | HSD17B10 (0.48) | ALDH1A1HPGDTSHRCYP1A2CYP3A4 | |
| SCHEMBL8330048 | 0.68 | MPL (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5107046-A | Adding urea to reaction mixture to suppress vapor pressure of hydrogen fluoride, diazotization, fluorination | MALLINCKRODT SPECIALTY CHEMICALS CO., INC. (US) | 1992-04-21 | — | — | US | disclosed |
| WO-1991017972-A1 | IMPROVED PROCESS FOR PREPARING AROMATIC FLUORIDES | MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) | 1991-11-28 | — | — | WO | disclosed |