Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11624287 | 0.97 | AHR (0.42) | AHRTP53TSHRHSD17B10CYP3A4 | |
| SCHEMBL1578248 | 0.91 | AHR (0.37) | AHRTP53TSHRHSD17B10CYP3A4 | |
| SCHEMBL826511 | 0.78 | CD44 (0.39) | TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL7253226 | 0.77 | HSD17B10 (0.48) | TSHRHSD17B10CYP3A4ALDH1A1 | |
| Fluoride Ion SCHEMBL9740670 | 0.77 | MEN1 (0.37) | TSHRCYP3A4IDO1ALDH1A1 | |
| SCHEMBL2916024 | 0.74 | AHR (0.43) | AHRTP53TSHRHSD17B10CYP3A4 | |
| SCHEMBL9847915 | 0.73 | MEN1 (0.35) | TSHRCYP3A4ALDH1A1 | |
| SCHEMBL10524196 | 0.73 | GAA (0.37) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL11331395 | 0.72 | GAA (0.36) | CYP3A4 | |
| SCHEMBL829160 | 0.72 | CD44 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107488113-B | Method for synthesizing o-aminobiphenyl compound | 上海泰禾国际贸易有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-110590597-A | Preparation method of aryltriazene compound | 浙江工业大学 | 2019-12-20 | — | — | CN | disclosed |
| US-20150191493-A1 | NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS | Universite de Bordeaux (FR) | 2015-07-09 | — | — | US | disclosed |
| CN-103517893-A | Method for synthesizing aminobiphenyl | BASF SE | 2014-01-15 | — | — | CN | disclosed |
| US-20130131074-A1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-05-23 | — | — | US | disclosed |
| US-8372837-B2 | Pyridone and pyridazone analogues as GPR119 modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-02-12 | — | — | US | disclosed |
| EP-2313395-B1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20110263548-A1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-10-27 | — | — | US | disclosed |
| CN-102159566-A | Pyridone and pyridazone analogues as gpr119 modulators | BRISTOL MYERS SQUIBB CO | 2011-08-17 | — | — | CN | disclosed |
| EP-2313395-A1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | Bristol-Myers Squibb Company (US) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010009183-A1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-01-21 | — | — | WO | disclosed |
| EP-0973724-B1 | NOVEL PROCESS FOR THE PREPARATION OF (+/-)3- (3,4-DICHLOROPHENYL)-2- DIMETHYLAMINO-2-METHYLPROPAN-1-OL OR CERICLAMINE (INN) | PARKE DAVIS (FR) | 2003-10-01 | — | — | EP | disclosed |
| US-6121491-A | Process for the preparation of (+/-)3-(3,4-dichlorophenyl)-2-dimethylamino-2-methylpropan-1-OL or cericlamine (INN) | WARNER-LAMBERT COMPANY (US) | 2000-09-19 | — | — | US | disclosed |
| EP-0973724-A1 | NOVEL PROCESS FOR THE PREPARATION OF (+/-)3- (3,4-DICHLOROPHENYL)-2- DIMETHYLAMINO-2-METHYLPROPAN-1-OL OR CERICLAMINE (INN) | PARKE-DAVIS (FR) | 2000-01-26 | — | — | EP | disclosed |
| EP-0931103-A1 | MONOMERS, OLIGOMERS AND POLYMERS WITH TERMINAL OXIRANE GROUPS, METHOD OF PREPARATION AND POLYMERISATION UNDER RADIATION EXPOSURE | UCB, S.A. (BE) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998045248-A1 | NOVEL PROCESS FOR THE PREPARATION OF (+/-)3- (3,4-DICHLOROPHENYL)-2- DIMETHYLAMINO-2-METHYLPROPAN-1-OL OR CERICLAMINE (INN) | JOUVEINAL (FR) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998014497-A1 | MONOMERS, OLIGOMERS AND POLYMERS WITH TERMINAL OXIRANE GROUPS, METHOD OF PREPARATION AND POLYMERISATION UNDER RADIATION EXPOSURE | UCB, S.A. (BE) | 1998-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131074-A1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | GPR119, GPR4, GPR3 | AHR 544/4885TP53 3695/4885TSHR 118/4885 |
| US-20110263548-A1 | PYRIDONE AND PYRIDAZONE ANALOGUES AS GPR119 MODULATORS | GPR119, GPR4, GPR3 | AHR 538/4885TP53 3660/4885TSHR 118/4885 |
| US-20150191493-A1 | NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS | NISCH, BRD7, BRSK2 | AHR 24/4885TP53 4855/4885TSHR 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.