Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | CHUK | O15111 | 1/20 | 0.30 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673163 | 0.98 | KDM4E (0.36) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL9675238 | 0.80 | — | — | |
| SCHEMBL29287589 | 0.72 | TSHR (0.36) | ALDH1A1MEN1KMT2AMAPK14 | |
| SCHEMBL9260906 | 0.71 | KDM4E (0.37) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL9674913 | 0.71 | KDM4E (0.40) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL8130541 | 0.71 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL2565757 | 0.70 | HCAR2 (0.52) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL12076049 | 0.69 | SCD (0.39) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL12602883 | 0.68 | CYP2C19 (0.39) | ALDH1A1KDM4EMEN1HPGDKMT2A | |
| SCHEMBL9891488 | 0.68 | MEN1 (0.44) | ALDH1A1KDM4EMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62084064-A | — | — | None | — | — | JP | disclosed |
| US-5082947-A | Chemical intermeidate for pesticides and drugs | SHIONOGI & CO., LTD. (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0220025-B1 | 3-PERFLUOROALKYL-5-HYDROXYISOXAZOLES | SHIONOGI & CO., LTD. (JP) | 1991-09-18 | — | — | EP | disclosed |
| EP-0220025-A1 | 3-perfluoroalkyl-5-hydroxyisoxazoles | SHIONOGI & CO., LTD. (JP) | 1987-04-29 | — | — | EP | disclosed |
| JP-S6284064-A | 3-PERFLUOROALKYL-5-HYDROXYISOXAZOLE | SHIONOGI & CO LTD | 1987-04-17 | — | — | JP | disclosed |