Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP7 | P09237 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7515779 | 0.89 | FABP5 (0.35) | EPHX2MDM4TP53FABP5FABP7 | |
| SCHEMBL7515772 | 0.89 | FABP5 (0.35) | EPHX2MDM4TP53FABP5FABP7 | |
| SCHEMBL14265225 | 0.78 | KMT2A (0.38) | EPHX2FABP5FABP7 | |
| SCHEMBL9740759 | 0.77 | KMT2A (0.37) | EPHX2MDM4TP53FABP5FABP7 | |
| SCHEMBL14282653 | 0.77 | KMT2A (0.38) | EPHX2FABP5FABP7 | |
| SCHEMBL9736075 | 0.77 | — | — | |
| SCHEMBL9734738 | 0.77 | — | — | |
| SCHEMBL9734966 | 0.77 | NTSR1 (0.37) | ACEMMENTSR1GRIN2BGRIN2C | |
| SCHEMBL16317480 | 0.77 | GRIN2B (0.54) | NTSR1GRIN2BGRIN2CADAM10MMP1 | |
| SCHEMBL14219500 | 0.76 | NTSR1 (0.36) | ACEMMENTSR1GRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166136-A | SPIROLACTAM CONTAINING PEPTIDES | GLAXO GROUP LIMITED (GB) | 1992-11-24 | — | — | US | disclosed |