Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740040 | 0.85 | ALOX5 (1.00) | ALOX5ALOX15MTNR1AMTNR1B | |
| SCHEMBL10513840 | 0.81 | ALOX5 (0.71) | ALOX5ALOX15MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL9740357 | 0.81 | ALOX5 (0.71) | ALOX5ALOX15 | |
| SCHEMBL9739471 | 0.76 | ALOX5 (0.82) | ALOX5ALOX15 | |
| SCHEMBL9739633 | 0.75 | ALOX5 (0.72) | ALOX5ALOX15MTNR1AMTNR1B | |
| SCHEMBL9740770 | 0.75 | ALOX5 (1.00) | ALOX5ALOX15VKORC1 | |
| SCHEMBL9742547 | 0.75 | ALOX5 (0.77) | ALOX5ALOX15 | |
| SCHEMBL9739761 | 0.74 | ALOX5 (0.59) | ALOX5ALOX15MTNR1AMTNR1B | |
| SCHEMBL9739632 | 0.73 | ALOX5 (0.85) | ALOX5ALOX15 | |
| SCHEMBL9739631 | 0.72 | ALOX5 (1.00) | ALOX5ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087638-A | Inhibitors of mammalian leukotriene biosynthesis | MERCK FROSST CANADA, INC. (CA) | 1992-02-11 | — | — | US | disclosed |
| EP-0338782-A1 | Benzofuran derivatives | MERCK FROSST CANADA INC. (CA) | 1989-10-25 | — | — | EP | disclosed |
| US-4863958-A | TREATING ALLERGIC CONDITIONS, ASTHMA, CARDIOVASCULAR DISORDERS, AND INFLAMMATION | MERCK FROSST CANADA, INC. (CA) | 1989-09-05 | — | — | US | disclosed |