Sugi Predict

Sugi Predict / Compounds / Methylamine

Methylamine

Methylamine

SCHEMBL9740790

CN.COc1ccc(CCCCl)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 1/20 0.59
▸ CALM1 P0DP23 1/20 0.58
▸ MAOB P27338 2/20 0.53
▸ AOC3 Q16853 2/20 0.52
▸ IGF1R P08069 1/20 0.51
▸ ALOX15 P16050 1/20 0.51
▸ ALOX5 P09917 1/20 0.49
▸ IDO1 P14902 3/20 0.48
▸ AGXT P21549 2/20 0.48
▸ ALDH1A1 P00352 1/20 0.47
▸ LMNA P02545 1/20 0.47
▸ SMN1; SMN2 Q16637 1/20 0.47
▸ SIGMAR1 Q99720 1/20 0.47
▸ TDP1 Q9NUW8 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1796734 0.96 CALM1 (0.62) TAAR1CALM1MAOBAOC3IGF1R
SCHEMBL5252007 0.90 CALM1 (0.60) TAAR1CALM1MAOBAOC3IGF1R
SCHEMBL8693900 0.88 CALM1 (0.58) TAAR1CALM1MAOBAOC3IGF1R
SCHEMBL8693901 0.88 CALM1 (0.58) TAAR1CALM1MAOBAOC3IGF1R
SCHEMBL6610916 0.88 CALM1 (0.58) TAAR1CALM1MAOBAOC3IGF1R
SCHEMBL365644 0.83 TAAR1 (0.61) TAAR1CALM1MAOBAOC3ALOX15
SCHEMBL244070 0.83 CALM1 (0.79) TAAR1CALM1MAOBAOC3IGF1R
SCHEMBL4254058 0.83 CALM1 (0.72) TAAR1CALM1MAOBAOC3IGF1R
SCHEMBL1797281 0.81 TAAR1 (0.59) TAAR1CALM1MAOBAOC3ALOX15
SCHEMBL17400406 0.81 CALM1 (0.69) TAAR1CALM1MAOBAOC3IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5175157-A Cardiovascular disorders BOEHRINGER INGELHEIM GMBH (DE) 1992-12-29 — — US disclosed