Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181005 | 0.81 | KDM4E (0.39) | MAPTKDM4ENQO2CYP19A1ALDH1A1 | |
| SCHEMBL9740069 | 0.75 | CYP1A2 (0.37) | MAPTPOLBTSHR | |
| SCHEMBL4477746 | 0.74 | CA12 (0.41) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL17658971 | 0.71 | MEN1 (0.40) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL9740158 | 0.69 | KDM4E (0.41) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL9740551 | 0.69 | KDM4E (0.35) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL29793327 | 0.68 | ACHE (0.52) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL1635785 | 0.68 | ACHE (0.52) | MAPTKDM4EMEN1KMT2APOLB | |
| SCHEMBL9740260 | 0.65 | PDE3B (0.40) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL5865329 | 0.65 | KDM4E (0.46) | MAPTKDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |