Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740885 | 0.77 | HPGD (0.34) | TSHRKMT2ATP53GAAMAPK1 | |
| SCHEMBL5143534 | 0.72 | BRD4 (0.36) | TSHRKMT2AGAATUBB4ATUBB | |
| SCHEMBL3903265 | 0.69 | CYP3A4 (0.50) | GAAMAPK1TUBB4ATUBBTUBA3C | |
| SCHEMBL578508 | 0.68 | SRC (0.57) | TSHRKMT2ATP53GAACCNB2 | |
| SCHEMBL12717984 | 0.68 | BRD4 (0.54) | KMT2AGAATUBB4ATUBBTUBA3C | |
| SCHEMBL16339494 | 0.67 | CYP11B1 (0.57) | TSHRKMT2ATP53GAAL3MBTL1 | |
| SCHEMBL10421507 | 0.67 | PLCG1 (0.49) | TSHRKMT2ATP53GAAMAPK1 | |
| SCHEMBL9739275 | 0.66 | — | — | |
| SCHEMBL29591948 | 0.66 | MAPT (0.52) | TSHRKMT2AGAAMEN1ALDH1A1 | |
| SCHEMBL1247901 | 0.66 | MAPT (0.52) | TSHRKMT2AGAAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221297-B1 | PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2018-08-22 | — | — | EP | claimed |
| EP-3221297-A1 | PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2017-09-27 | — | — | EP | claimed |
| WO-2016079684-A1 | PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2016-05-26 | — | — | WO | claimed |
| WO-2019202611-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | METROCHEM API PVT (IN) | 2019-10-24 | — | — | WO | disclosed |
| EP-3221297-B1 | PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2018-08-22 | — | — | EP | disclosed |
| EP-3221297-A1 | PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2017-09-27 | — | — | EP | disclosed |
| EP-3221297-A1 | PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES | Richter Gedeon Nyrt. (HU) | 2017-09-27 | — | — | EP | disclosed |
| WO-2016079684-A1 | PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2016-05-26 | — | — | WO | disclosed |
| WO-2016079684-A1 | PROCESS FOR THE SYNTHESIS OF BENZAZEPINE DERIVATIVES | RICHTER GEDEON NYRT. (HU) | 2016-05-26 | — | — | WO | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |