Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.31 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MMP12 | P39900 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740835 | 0.77 | TSHR (0.40) | MAPK1ALDH1A1TP53KMT2AMEN1 | |
| SCHEMBL9739275 | 0.69 | — | — | |
| SCHEMBL1247901 | 0.69 | MAPT (0.52) | HSD17B10ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL29591948 | 0.69 | MAPT (0.52) | HSD17B10ALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL20050453 | 0.68 | GSK3B (0.41) | ALDH1A1SMN1; SMN2MAPTGAAKDM4E | |
| SCHEMBL22400697 | 0.67 | PKM (0.34) | ALDH1A1MAPTGAA | |
| SCHEMBL3195465 | 0.65 | NPC1 (0.30) | MAPTRAB9A | |
| SCHEMBL17348364 | 0.64 | CYP11B1 (0.42) | HPGDMAPK1HSD17B10POLBALDH1A1 | |
| SCHEMBL1436084 | 0.64 | GRIA1 (0.53) | HPGDMAPK1HSD17B10POLBEPHX2 | |
| SCHEMBL1305583 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |