Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.42 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4473071 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2CTSLCTSS | |
| SCHEMBL6216286 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2CTSLCTSS | |
| SCHEMBL5640402 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2CTSLCTSS | |
| SCHEMBL13590480 | 0.78 | TOP2A (0.54) | MEN1KMT2ATPSAB1PRSS1PLG | |
| SCHEMBL9765305 | 0.78 | LMNA (0.51) | MEN1KMT2ALMNAMIFSMN1; SMN2 | |
| SCHEMBL27268626 | 0.77 | LMNA (0.54) | LMNASMN1; SMN2CTSLCTSS | |
| SCHEMBL20434509 | 0.76 | SCN1A (0.48) | TPSAB1PRSS1PLGLMNASMN1; SMN2 | |
| SCHEMBL24334713 | 0.76 | HTT (0.57) | MEN1KMT2ATPSAB1PRSS1LMNA | |
| SCHEMBL452919 | 0.75 | MEN1 (0.55) | MEN1KMT2ALMNAMIFESR1 | |
| SCHEMBL27635293 | 0.75 | MEN1 (0.55) | MEN1KMT2ALMNAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142056-A | Human immunodeficiency virus protease inhibitor | ABBOTT LABORATORIES (US) | 1992-08-25 | — | — | US | disclosed |