Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 3/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13073758 | 0.93 | LMNA (0.55) | LMNASMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL13073762 | 0.93 | LMNA (0.55) | LMNASMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL6557654 | 0.89 | CYP3A4 (0.49) | LMNASMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL6185436 | 0.89 | LMNA (0.49) | LMNASMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL8079357 | 0.87 | CYP3A4 (0.47) | LMNASMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL5988161 | 0.86 | PLAU (0.50) | LMNASMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL9765290 | 0.85 | PTPN1 (0.55) | HTTCTSKCTSS | |
| SCHEMBL5328614 | 0.84 | PPARG (0.50) | CTSKCTSSCTSLSYKCTSB | |
| SCHEMBL9513721 | 0.84 | LMNA (0.44) | LMNASMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL13570108 | 0.84 | KLK1 (0.49) | LMNASMN1; SMN2KLK1HTTCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255728-B1 | PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE | TANABE SEIYAKU CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4866196-A | ANTICOAGULANTS | TANABE SEIYAKU CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| EP-0255728-A2 | Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use | TANABE SEIYAKU CO., LTD. (JP) | 1988-02-10 | — | — | EP | disclosed |