Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740214 | 0.84 | CYP1A2 (0.61) | CYP1A2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL8538892 | 0.80 | CYP1A2 (0.62) | CYP1A2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL9739732 | 0.78 | CYP1A2 (0.50) | CYP1A2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL9738135 | 0.75 | CYP1A2 (0.59) | CYP1A2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL9741145 | 0.73 | CYP1A2 (0.53) | CYP1A2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL2984390 | 0.73 | MAPT (0.59) | CYP1A2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL9763452 | 0.73 | CYP1A2 (0.53) | CYP1A2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL3791688 | 0.73 | CYP1A2 (0.72) | CYP1A2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL9640545 | 0.73 | CYP1A2 (1.00) | CYP1A2ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL9739022 | 0.72 | CYP1A2 (0.56) | CYP1A2ALDH1A1MAPTKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126454-A | PROCESS FOR THE PREPARATION OF SULPHONYLISOUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |