Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL10687864 | 0.90 | ALDH1A1 (0.53) | CYP1A2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL2984390 | 0.88 | MAPT (0.59) | CYP1A2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL2702801 | 0.84 | CYP1A2 (0.72) | CYP1A2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL3363746 | 0.82 | KMT2A (0.53) | CYP1A2ALDH1A1KDM4EKMT2AGLA | |
| SCHEMBL3367290 | 0.80 | KMT2A (0.49) | CYP1A2ALDH1A1KDM4EKMT2AGLA | |
| SCHEMBL3791688 | 0.80 | CYP1A2 (0.72) | CYP1A2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL3364492 | 0.80 | KMT2A (0.49) | CYP1A2ALDH1A1KDM4EKMT2AGLA | |
| SCHEMBL9740893 | 0.80 | CYP1A2 (0.57) | CYP1A2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL11795513 | 0.79 | POLB (0.48) | CYP1A2ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL9763452 | 0.79 | CYP1A2 (0.53) | CYP1A2ALDH1A1MAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467251-B1 | Process for the preparation of N-alkylsulfonylaminosulfonyl ureas | HOECHST SCHERING AGREVO GMBH (DE) | 1998-06-03 | — | — | EP | disclosed |
| US-5155222-A | PROCESS FOR THE PREPARATION OF N-ALKYLSULFONYLAMINOSULFONYLUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-13 | — | — | US | disclosed |
| EP-0279366-B1 | PROCESS FOR THE PREPARATION OF PYRIMIDINES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0467251-A2 | Process for the preparation of N-alkylsulfonylaminosulfonyl ureas | Hoechst Schering AgrEvo GmbH (DE) | 1992-01-22 | — | — | EP | disclosed |
| US-4960887-A | REACTING PROPANEDIIMIDATE WITH CARBONIC ACID IMINEDERIVATIVE | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0279366-A2 | Process for the preparation of pyrimidines | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-24 | — | — | EP | disclosed |