Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740214 | 0.89 | CYP1A2 (0.61) | CYP1A2HTTTSHRSMN1; SMN2MAPT | |
| SCHEMBL9739707 | 0.87 | KMT2A (0.47) | CYP1A2HTTMAPTKMT2AMEN1 | |
| SCHEMBL10503870 | 0.82 | CYP1A2 (0.46) | CYP1A2HTTTSHRSMN1; SMN2MAPT | |
| SCHEMBL9741145 | 0.81 | CYP1A2 (0.53) | CYP1A2HTTTSHRSMN1; SMN2MAPT | |
| SCHEMBL9129851 | 0.81 | CYP1A2 (0.61) | CYP1A2HTTTSHRSMN1; SMN2MAPT | |
| SCHEMBL9368434 | 0.79 | CYP1A2 (0.59) | CYP1A2HTTTSHRSMN1; SMN2MAPT | |
| SCHEMBL9741185 | 0.79 | KMT2A (0.47) | CYP1A2HTTTSHRMAPTLMNA | |
| SCHEMBL9740893 | 0.78 | CYP1A2 (0.57) | CYP1A2HTTTSHRSMN1; SMN2MAPT | |
| SCHEMBL10415643 | 0.78 | MAPT (0.49) | CYP1A2HTTTSHRSMN1; SMN2MAPT | |
| SCHEMBL10616011 | 0.78 | CYP1A2 (0.57) | CYP1A2HTTTSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126454-A | PROCESS FOR THE PREPARATION OF SULPHONYLISOUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |