Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 12/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 11/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6007698 | 0.90 | AGTR1 (0.64) | AGTR1AGTR2MME | |
| SCHEMBL6005823 | 0.88 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL6006007 | 0.85 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8842083 | 0.84 | AGTR1 (0.50) | AGTR1AGTR2MME | |
| SCHEMBL8842007 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2MME | |
| SCHEMBL9737737 | 0.84 | BRS3 (0.42) | AGTR1AGTR2MME | |
| SCHEMBL9739525 | 0.83 | AGTR1 (0.54) | AGTR1AGTR2MME | |
| SCHEMBL9528906 | 0.83 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL8842055 | 0.83 | AGTR1 (0.50) | AGTR1AGTR2MME | |
| SCHEMBL9532242 | 0.82 | BRS3 (0.41) | AGTR1AGTR2MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992004335-A2 | RENAL-SELECTIVE BIPHENYLALKYL 1H-SUBSTITUTED-1,2,4-TRIAZOLE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1992-03-19 | — | — | WO | claimed |