Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9197538 | 0.74 | CDK1 (0.34) | HPGDSMN1; SMN2HTT | |
| SCHEMBL9191384 | 0.74 | SLC6A2 (0.42) | HPGDSMN1; SMN2HTT | |
| SCHEMBL27320524 | 0.70 | PI4KA (0.49) | EGFRKDRSRC | |
| SCHEMBL9199457 | 0.64 | CYP1A2 (0.35) | CYP1A2CYP2D6MAPK1 | |
| SCHEMBL6654114 | 0.62 | ATM (0.52) | ALDH1A1MAPTHTT | |
| SCHEMBL29439090 | 0.60 | ABCG2 (0.42) | EGFRRETMAPTFLT3MKNK1 | |
| SCHEMBL22717857 | 0.60 | ABCG2 (0.42) | EGFRRETMAPTFLT3MKNK1 | |
| SCHEMBL31325644 | 0.59 | RAB9A (0.63) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL22717643 | 0.59 | RAB9A (0.63) | ALDH1A1HPGDSMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL14185394 | 0.59 | FLT3 (0.50) | RETMAPTGAAMAPK1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155098-A | Analgesics, anticonvulsants | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1992-10-13 | — | — | US | disclosed |